Type 3 polyglandular autoimmune syndrome: association of lada, hashimoto's thyroiditis and celiac syndrome
نویسندگان
چکیده
Background Polyglandular Autoimmune Syndrome (PAS) was first described by Neufeld et al in 1980 as a syndrome involving multiple organs with endocrine disorders with hypofunction of the involved organ. The peak age-specific incidence occurs between 20 to 60 yrs. of age. Type 3 Polyglandular Autoimmune Syndrome is defined as autoimmune thyroiditis in association with Type 1 Diabetes; Type 3A when associated to Sarcoidosis or Celiac Disease, associated to Pernicious Anemia on Type 3B, or with Vitiligo or Alopecia on Type 3C.
منابع مشابه
Erythema annulare centrifugum: association with autoimmune polyglandular syndrome type 1
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A female patient demonstrating a previously not reported constellation of polyglandular autoimmune syndrome type III (including autoimmune thyroiditis, Graves' ophthalmopathy, insulin-dependent diabetes mellitus and vitiligo), coeliac disease and sarcoidosis is described. This may be a random association but might also indicate a common immunological and/or genetic disturbance.
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Autoimmune polyglandular syndrome is a constellation of signs and symptoms of simultaneous insufficiencies of several endocrine glands. Autoimmune polyglandular syndrome type 2 (APS 2) may be diagnosed when the adrenocortical insufficiency is associated with an autoimmune thyroid disease (Hashimoto's thyroiditis or Graves' disease), and/or insulin-dependent diabetes mellitus. Turner syndrome is...
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Type 1 diabetes mellitus (T1DM) results from autoimmune destruction of insulin-producing beta cells and is characterised by the presence of insulitis and &and beta-cell autoantibodies. Up to one third of patients develop an autoimmune polyglandular syndrome. Fifteen to 30% of T1DM subjects have autoimmune thyroid disease (Hashimoto's or Graves' disease), 5 to 10% are diagnosed with autoimmune g...
متن کاملEpidemiological and clinical peculiarities of polyglandular syndrome type 3 in pediatric age
BACKGROUND Although the autoimmune polyglandular syndrome type 3 (APS-3) is the commonest APS that may be encountered in pediatric age, last year literature includes only few studies aiming to specifically ascertain the clinical spectrum of APS-3 in childhood and adolescence. Aims of these study were: a) to ascertain how many young patients with apparently isolated Hashimoto's thyroiditis (HT) ...
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عنوان ژورنال:
دوره 7 شماره
صفحات -
تاریخ انتشار 2015